This is not evident from experimental structures. inhibitors of BoNT/A targeting the exosites. Hits C1 and C2 showed non-competitive inhibition and likely target the – and -exosites, respectively. The identified exosite inhibitors may provide novel candidates for structure-based development of therapeutics against BoNT/A intoxication. neurotoxins (BoNTs) are classified as Tier … Continue reading This is not evident from experimental structures